The Grand Harbour or, in Maltese, Il-Port il-Kbir, lies mainly beneath Valletta, the capital city of Malta, and the Three Cities of Cospicua, Vittoriosa and Senglea.

The Harbour mouth faces North East. Sheltered at the north by St.Elmo’s Point breakwater, Ricasoli Breakwater arm is found at the south. Its North West shore is formed by the Sciberras peninsula (over which Valletta, and its suburb Floriana, were built). This peninsula also divides the Grand Harbour from a second parallel natural harbour, Marsamxett Harbour. The main waterway of Grand Harbour continues inland to Marsa. The south eastern shore of the Harbour is formed by a number of inlets and headlands, principally Rinella Creek, Kalkara Creek, Dockyard Creek, and French Creek, which are covered by Kalkara and the Three Cities: Cospicua, Vittoriosa, and Senglea.

The Port of Valletta, a natural deep-water harbour, extends for about 3.6 kilometres inland. Its two-arm breakwater renders it a safe, all-weather port throughout the year, open on a 24 hour basis, although entrance may be restricted during strong Easterly winds. The Port of Valletta is a multi-purpose port equipped to offer a large spectrum of maritime services including:

• - various cruise/ferry and cargo berths
• - specialised grain and cement silos
• - petroleum installations, bunkering facilities
• - ship repair and building yards
• - ship chandelling
• - reception facilities
• - other ship related services

Warehousing and open storage facilities are available throughout the port area.